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A new role for cryptochrome in a Drosophila circadian oscillator
A new role for cryptochrome in the internal clock of fruit flies
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Abstract
Cryptochrome (CRY) contributes to oscillator function and physiological output rhythms in the antenna of Drosophila.
- CRY is involved in circadian clock function in both the brain and peripheral tissues of Drosophila.
- A Drosophila mutant lacking CRY shows intact central circadian mechanisms but disrupted peripheral oscillators.
- The arrhythmicity observed in peripheral oscillators could result from a loss of light entrainment or CRY's role in the oscillator.
- CRY affects olfactory responses in Drosophila antennae during and after light-dark cycle entrainment and after light input is removed.
- These findings indicate that there are fundamental differences between how central and peripheral oscillators operate in Drosophila.
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