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Abstract
A novel approach using synthetic mRNA encoding hGH has been developed to enable endogenous hormone production.
- Human growth hormone deficiency is commonly treated with daily injections of recombinant human growth hormone.
- Current treatments do not fully replicate natural hormone secretion patterns.
- Synthetic mRNA is designed to prompt the body to produce its own growth hormone.
- The synthetic mRNA is encapsulated in lipid nanoparticles for delivery.
- This method could potentially offer a new way to address growth hormone deficiency.
Simplified