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Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis
Dexmedetomidine's impact on thinking problems after planned non-heart surgery in older patients
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Abstract
The perioperative intravenous use of dexmedetomidine significantly reduced the incidence of and in 4,376 senile patients.
- Dexmedetomidine is associated with a lower incidence of neurocognitive disturbances after elective non-cardiac surgery compared to saline.
- Patients receiving dexmedetomidine experienced a higher likelihood of developing bradycardia and hypotension.
- No significant differences were found between dexmedetomidine and control groups regarding nausea, vomiting, or mortality rates.
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Key numbers
0.53
Reduction in Incidence
Risk ratio for the incidence of compared to control.
1.39
Increase in Bradycardia Risk
Risk ratio for bradycardia incidence compared to control.