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A Comprehensive Analysis of Diabetic Complications and Advances in Management Strategies
Diabetes Complications and New Ways to Manage Them
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Abstract
Diabetes mellitus, particularly type 2 diabetes mellitus, affects millions globally and is associated with severe complications that impact quality of life and increase mortality.
- Diabetes predisposes individuals to microvascular and macrovascular complications.
- Key mechanisms involved in diabetic complications include atherosclerosis, insulin resistance, chronic inflammation, and endothelial dysfunction.
- Recent therapeutic advancements, such as SGLT2 inhibitors and GLP-1 receptor agonists, offer benefits beyond glycemic control.
- These therapies may provide cardiovascular and renal protection.
- Differences in insulin secretion capacity between Western and Asian patients, including Japanese patients, are considered for developing treatment strategies.
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