Full text is available at the source.
DNA Methylation Clocks in Aging: Categories, Causes, and Consequences
DNA Methylation Clocks in Aging: Types, Causes, and Effects
AI simplified
Abstract
Age-associated changes to the mammalian DNA methylome are linked to diseases of aging.
- Chronological age can be measured using specific patterns of DNA methylation, known as the DNA methylation clock.
- The biological clock, which reflects health status, may also be influenced by DNA methylation.
- Understanding the relationship between chronological and biological clocks may reveal underlying mechanisms of aging.
- DNA methylation could serve as a biomarker for assessing disease risk and healthy aging.
- These findings suggest that targeting DNA methylation may offer new avenues for promoting longevity.
AI simplified