Effects of early, late and self-selected time-restricted eating on visceral adipose tissue and cardiometabolic health in participants with overweight or obesity: a randomized controlled trial

A total of 197 participants were randomized to evaluate the impact of different time-restricted eating schedules on visceral adipose tissue changes.

• No significant differences in visceral adipose tissue changes were observed between early, late, or self-selected time-restricted eating and usual care.
• Mean differences in visceral adipose tissue for early TRE, late TRE, and self-selected TRE compared to usual care were -4%, -6%, and -3%, respectively.
• All comparisons among the time-restricted eating groups yielded p-values greater than or equal to 0.99.
• Adherence to the time-restricted eating schedules was high, ranging from 85% to 88%.
• No serious adverse events were reported; however, five participants experienced mild adverse events.
• These results indicate that time-restricted eating does not provide additional benefits for reducing visceral adipose tissue compared to a Mediterranean diet.

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