Armodafinil’s effects on symptoms late in the work shift and overall functioning in people with shift work sleepiness

Patients receiving armodafinil showed significant improvements in late-in-shift clinical condition, wakefulness, and overall functioning compared to placebo.

• Armodafinil may reduce sleepiness experienced by patients with shift work disorder during late-night shifts.
• Improvements were observed in clinical condition as measured by Clinical Global Impression-Change.
• Overall functioning of patients, assessed by the Global Assessment of Functioning score, was also enhanced.
• Armodafinil was generally well tolerated among participants in the study.

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