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Abstract
Diabetic nephropathy is the leading cause of end-stage renal disease.
- Core factors in diabetic nephropathy include glomerular and tubular injury, mitochondrial dysfunction, and impaired mitophagy.
- FUNDC1 has been identified as a crucial receptor for the process of mitophagy.
- The regulatory mechanism of FUNDC1 in diabetic nephropathy is not well understood.
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