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Abstract
Elastin-derived fragments may function as systemic drivers of aging and inflammation.
- The extracellular matrix undergoes significant changes with age.
- Elastin-derived fragments are identified as bioactive molecules, known as matrikines.
- These fragments may actively contribute to inflammation and aging processes, rather than merely resulting from tissue breakdown.
- Recent findings suggest that elastin-derived fragments play a role in mediating systemic aging.
- The insights gained could inform new therapeutic strategies for treating age-related diseases.
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