Endocrinology and metabolism clinics of North America

New Evidence That Blood Sugar and Hormone Drugs May Protect Heart and Kidneys in People with Type 1 Diabetes

Updated

Abstract

Sodium-glucose cotransporter inhibitors, glucagon-like peptide 1 receptor agonists, and mineralocorticoid receptor blockers may provide substantial cardiovascular and renal protection in type 1 diabetes.

  • These newer agents have revolutionized treatment for type 2 diabetes.
  • Data on the effects of these agents in type 1 diabetes is summarized.
  • There is an emphasis on the need for more long-term studies.
  • Future studies could assess the impact of these agents on cardiovascular risk.

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Full Text

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Funding

Competing interests

Disclosure S. Fernandes has nothing to disclose. B. Hettinger has nothing to disclose. L. Ang has nothing to disclose. R. Pop-Busui received research grant support has received research funding to her institutions from NIDDK, United States, Breakthrough T1D, United States, Lexicon Pharmaceuticals, Novo Nordisk, Denamrk, and Bayer, Germany; and consulting fees from Averitas Pharma, Lexicon Pharmaceuticals, Novo Nordisk, Nevro, Roche, Vertex, and Viatris.
PubMed

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