Emerging Multifunctional Wearable Sensors: Integrating Multimodal Sweat Analysis and Advanced Material Technologies for Next-Generation Health Monitoring

Mar 31, 2025ACS sensors

New Wearable Sensors Combining Sweat Analysis and Advanced Materials for Improved Health Monitoring

AI simplified

Circadian Biology on OpenScience ↗PubMed ↗DOI ↗

Abstract

Sweat contains diverse biomarkers that can reflect physiological states in real time.

Multimodal wearable sensors can monitor biomarkers such as glucose, sodium, and cortisol, as well as physical parameters like movement and temperature.
These sensors utilize advanced materials including hydrogels, MXenes, and graphene to enhance their functionality.
Innovations in materials and structural designs may improve the effectiveness of health monitoring applications, such as metabolic health management and stress detection.
Challenges remain in integrating signals, processing data, and managing power for continuous monitoring.
Advancements in self-powered systems and energy harvesting technologies could support real-time health monitoring.

AI simplified

Sweat, a noninvasive and readily accessible biofluid, offers significant potential in health monitoring through its diverse biomarker profile, including electrolytes, metabolites, and hormones, which reflect physiological states in real time. Multimodal wearable sensors, integrating chemical, physical, and thermal sensing capabilities, have emerged as transformative tools for capturing these biomarkers alongside additional physiological signals. By combining advanced materials such as hydrogels, MXenes, and graphene with innovative structural designs, these sensors enable simultaneous monitoring of biomarkers (e.g., glucose, sodium, and cortisol) alongside parameters like movement and temperature. This Review systematically explores the classification and design of multimodal sensors, emphasizing their ability to address health monitoring challenges across applications including metabolic health management, stress detection, and hydration assessment. Key innovations in functional materials, such as conductive hydrogels and biomimetic structures, are discussed alongside challenges in signal integration, data processing, and power management. Additionally, advancements in self-powered systems and energy harvesting technologies have been highlighted as critical enablers for continuous, real-time monitoring. The Review concludes with a perspective on future directions, emphasizing the need for scalable manufacturing techniques, artificial intelligence integration, and standardized frameworks to enhance sensor functionality and adoption. Multimodal wearable sensors, by seamlessly integrating health data into daily life, hold the promise of transforming personalized healthcare, enabling proactive management of health and wellness through noninvasive, comprehensive, and real-time monitoring.

Full Text

Full text is available at the source.

View full text (PDF) ↗View full text ↗

Emerging Multifunctional Wearable Sensors: Integrating Multimodal Sweat Analysis and Advanced Material Technologies for Next-Generation Health Monitoring

Abstract

Full Text

You found one interesting study. We’ll send the next 7.

what lands in your inbox each week:

Recent issues from the circadian biology brief

Abstract

Full Text

Related papers

You found one interesting study. We’ll send the next 7.

what lands in your inbox each week:

Recent issues from the circadian biology brief