Improving female fertility by using biomaterials to repair fallopian tubes

A review of 42 studies indicates that biomaterials and organoid systems may enable the regeneration of uterine tubes, which are crucial for natural conception.

• Natural polymers like collagen and decellularized extracellular matrix can create biocompatible scaffolds that mimic the body's own environment.
• Synthetic polymers allow for control over mechanical properties and reproducibility in tissue engineering applications.
• Hydrogels create a 3D environment that supports important biological processes such as cell differentiation and embryo development.
• Uterine tube-derived organoids can serve as relevant models for understanding diseases and testing drugs.
• Advancements in 3D and magnetic bioprinting have led to artificial uterine tube models that closely resemble natural tissue structure.

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