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Abstract
is a progressive age-related disorder that leads to significant loss of skeletal muscle mass, strength, and physical function.
- Sarcopenia is closely associated with aging and physical inactivity, impacting mobility and quality of life in older adults.
- Exercise is recognized as an effective non-drug approach to manage sarcopenia, but the molecular mechanisms involved are not fully understood.
- are signaling molecules released during physical exercise that mediate the beneficial effects of exercise on the body.
- These molecules are secreted by various tissues and play important roles in muscle regeneration, inflammation, and metabolic balance.
- The secretion and function of exerkines are influenced by the type, intensity, and duration of exercise.
- Understanding exerkine signaling could provide new therapeutic options for individuals who cannot regularly participate in physical activity.
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