We can’t show the full text here under this license. Use the link below to read it at the source.
Exercise, Exerkines, and Sarcopenia
How Exercise-Related Substances Affect Muscle Loss with Aging
AI simplified
Abstract
is a progressive age-related disorder that leads to significant loss of skeletal muscle mass, strength, and physical function.
- Sarcopenia is closely associated with aging and physical inactivity, impacting mobility and quality of life in older adults.
- Exercise is recognized as an effective non-drug approach to manage sarcopenia, but the molecular mechanisms involved are not fully understood.
- are signaling molecules released during physical exercise that mediate the beneficial effects of exercise on the body.
- These molecules are secreted by various tissues and play important roles in muscle regeneration, inflammation, and metabolic balance.
- The secretion and function of exerkines are influenced by the type, intensity, and duration of exercise.
- Understanding exerkine signaling could provide new therapeutic options for individuals who cannot regularly participate in physical activity.
AI simplified
Key numbers
3 to 24%
Prevalence
Prevalence among adults aged 65 years and older in Korea.
up to 100-fold
Increased IL-6 Levels
Observed following acute exercise.
150 to 300 minutes
Exercise Recommendations
Recommended weekly aerobic activity for older adults by WHO.