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Abstract
Head and neck squamous cell carcinoma (HNSCC) significantly impairs patients' quality of life.
- Neoadjuvant immuno-chemotherapy may provide survival benefits but is associated with treatment-related toxicities.
- Common toxicities include fatigue, sleep disturbances, and functional decline.
- Exercise therapy has been effective in enhancing quality of life in patients with other types of cancer.
- The impact of exercise therapy on HNSCC patients receiving neoadjuvant therapy remains largely unstudied.
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