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Abstract
High levels of blood cholesterol are a major modifiable risk factor for cardiovascular disease (CVD).
- Statins are the preferred treatment for preventing CVD but may not be tolerated by all high-risk patients.
- Some individuals cannot achieve desired treatment outcomes even with maximum statin doses.
- Ezetimibe is a medication that selectively inhibits cholesterol absorption, but its effects on CVD events are unclear.
- Clinical study results regarding ezetimibe's efficacy and safety for preventing CVD and mortality have been inconsistent.
- A thorough evaluation of ezetimibe is necessary to determine its role in CVD prevention.
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