Link between gut inflammation and movement and non-movement symptoms in Parkinson's disease and similar disorders

Fecal calprotectin levels may indicate gut-brain axis dysfunction in Parkinson's disease.

• Elevated fecal calprotectin is associated with intestinal inflammation.
• The study focuses on idiopathic Parkinson's disease and atypical parkinsonian syndromes, including progressive supranuclear palsy and multiple system atrophy.
• There may be a relationship between fecal calprotectin levels and both motor and non-motor features of Parkinson's disease.
• Findings could provide insights into the role of gut inflammation in parkinsonian disorders.

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