Unveiling the therapeutic potential of ferroptosis in lung cancer: a comprehensive bibliometric analysis and future therapeutic insights

Apr 10, 2025Discover oncology

The potential of ferroptosis as a treatment for lung cancer: a detailed analysis and future therapy ideas

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Abstract

research in lung cancer has shifted focus towards clinical applications, particularly targeting GPX4.

  • The analysis highlights a transition from basic mechanisms to clinical applications in ferroptosis research.
  • Key areas of interest include the development of GPX4-targeted therapies and combination treatments.
  • Increased international collaboration has positioned the United States and China as leading contributors.
  • Interdisciplinary studies have provided new insights into the interaction between ferroptosis, the tumor microenvironment, and the immune system.
  • Ferroptosis may help overcome drug resistance by regulating iron-dependent lipid peroxidation.
  • Future research is suggested to focus on translating ferroptosis-based therapies into personalized medicine for lung cancer.

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Key numbers

1664
Total Articles
Total articles retrieved for analysis on and lung cancer.
3
Leading Countries
Top countries maintaining high research cooperation in studies.

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