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Abstract
Folic acid (FA) availability may influence circadian clock gene regulation in head and neck squamous cell carcinoma (HNSCC).
- FA is involved in one-carbon metabolism, DNA synthesis, and DNA methylation.
- The study explores the potential effects of FA oversupplementation on cell viability in HNSCC cells.
- FA availability may affect the expression and methylation of circadian clock genes.
- Circadian clock gene regulation could be influenced by the availability of methyl donors.
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