Unique Presentation of the Follicular Occlusion Tetrad: A Case Report and Review of the Literature

Sep 19, 2025Cureus

A Rare Combined Case of Four Related Skin Blockage Disorders: Report and Review

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Abstract

A 43-year-old female patient exhibited all four conditions of the follicular occlusion tetrad after 36 years of symptoms.

  • The follicular occlusion tetrad consists of hidradenitis suppurativa, acne conglobata, dissecting cellulitis of the scalp, and pilonidal cyst.
  • The patient had a history of treatment with ciprofloxacin, spironolactone, and salicylic acid prior to the current presentation.
  • This case is the first report of the complete tetrad in a female patient.
  • The patient was noted to be on semaglutide for weight loss at the time of presentation.
  • A literature review suggests a potential link between the follicular occlusion tetrad and obesity, indicating a need for further investigation into treatment options.

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