Journal of ethnopharmacology

Forsythoside A may ease high blood pressure kidney damage by boosting cell cleanup and blocking cell death through the ASCL1-CCNB1/mTOR pathway

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Abstract

Forsythoside A (FTA) is associated with potent anti-inflammatory and antioxidant activities.

  • Forsythiae Fructus is traditionally used in TCM for inflammatory conditions.
  • Hypertensive nephropathy is linked to chronic inflammation and oxidative stress.
  • FTA may inhibit the progression of hypertensive nephropathy.
  • The mechanisms underlying FTA's effects on hypertensive nephropathy remain unclear.

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