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Tracking the genetics and vaccine response to the main SARS-CoV-2 XBB variant in Rio Grande do Sul
Updated
Abstract
In March 2023, XBB accounted for 83.3% of SARS-CoV-2 cases in Rio Grande do Sul, Brazil.
- 143 samples were identified as XBB, while 586 were classified as other Omicron lineages.
- 97.7% of patients infected with XBB recovered, with a low mortality rate of 2.3%.
- 59.5% of previously infected and vaccinated patients experienced reinfection with XBB.
- 54% of individuals had an interval of over one year since their last vaccine dose before XBB infection.
- 90 mutations associated with immune resistance were identified in the XBB lineage, particularly in the Spike protein region.
Simplified
Key numbers
83.3%
Dominance of XBB
Percentage of SARS-CoV-2 cases attributed to XBB in March 2023.
59.5%
Reinfection Rate
Percentage of individuals reinfected with XBB among those previously infected.
90
Mutation Count
Total mutations found in the XBB genome.