Glioblastoma chemotherapeutic agents used in the clinical setting and in clinical trials: Nanomedicine approaches to improve their efficacy

Apr 3, 2020International journal of pharmaceutics

Using Nanomedicine to Improve Chemotherapy Drugs for Glioblastoma in Patients and Clinical Trials

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Abstract

Glioblastoma multiforme has the lowest median overall survival among all malignant brain tumors.

  • Current therapeutic strategies for glioblastoma are insufficient, necessitating novel approaches.
  • Nanomedicine may enhance drug delivery to the brain, improving treatment outcomes.
  • This review focuses on nanomedicine-based delivery strategies tested in animal models.
  • Drug candidates currently in clinical use or trials may benefit from these nanotechnology approaches.
  • Future perspectives suggest that nanocarriers could play a significant role in glioblastoma treatment.

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