Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Sep 13, 2018CA: a cancer journal for clinicians

Worldwide estimates of new cases and deaths for 36 cancers in 185 countries in 2018

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Abstract

An estimated 18.1 million new cancer cases and 9.6 million cancer deaths are projected globally for 2018.

Lung cancer accounts for 11.6% of new cases and is the leading cause of cancer death at 18.4%.
Female breast cancer ranks second in incidence and mortality, with 11.6% of cases and lower death rates compared to lung cancer.
Prostate cancer and colorectal cancer are significant in males for incidence (7.1% and 6.1%, respectively) but vary in mortality, with liver and stomach cancers being more prevalent.
Cervical cancer is the fourth most common cancer in both incidence and mortality among females.
Cancer incidence and mortality rates show significant geographic variability, influenced by economic development and lifestyle factors.
Most low- and middle-income countries lack high-quality cancer registry data, which hampers effective cancer control planning.

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This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions. There will be an estimated 18.1 million new cancer cases (17.0 million excluding nonmelanoma skin cancer) and 9.6 million cancer deaths (9.5 million excluding nonmelanoma skin cancer) in 2018. In both sexes combined, lung cancer is the most commonly diagnosed cancer (11.6% of the total cases) and the leading cause of cancer death (18.4% of the total cancer deaths), closely followed by female breast cancer (11.6%), prostate cancer (7.1%), and colorectal cancer (6.1%) for incidence and colorectal cancer (9.2%), stomach cancer (8.2%), and liver cancer (8.2%) for mortality. Lung cancer is the most frequent cancer and the leading cause of cancer death among males, followed by prostate and colorectal cancer (for incidence) and liver and stomach cancer (for mortality). Among females, breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death, followed by colorectal and lung cancer (for incidence), and vice versa (for mortality); cervical cancer ranks fourth for both incidence and mortality. The most frequently diagnosed cancer and the leading cause of cancer death, however, substantially vary across countries and within each country depending on the degree of economic development and associated social and life style factors. It is noteworthy that high-quality cancer registry data, the basis for planning and implementing evidence-based cancer control programs, are not available in most low- and middle-income countries. The Global Initiative for Cancer Registry Development is an international partnership that supports better estimation, as well as the collection and use of local data, to prioritize and evaluate national cancer control efforts. CA: A Cancer Journal for Clinicians 2018;0:1-31. © 2018 American Cancer Society.

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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

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