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Recent trends in GLP-1 RA and SGLT2i use among people with type 2 diabetes and atherosclerotic cardiovascular disease in the USA
Recent trends in the use of diabetes drugs GLP-1 receptor agonists and SGLT2 inhibitors among people with type 2 diabetes and heart artery disease in the USA
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Abstract
Prevalent use of GLP-1 receptor agonists and/or SGLT2 inhibitors increased from 9.2% in 2018 to 27.1% in 2022 among patients with type 2 diabetes and atherosclerotic cardiovascular disease.
- Eligible annual patient numbers for the study ranged from 279,474 to 348,997 during the analysis period.
- The use of GLP-1 receptor agonists alone rose from 5.2% to 9.9% between 2018 and 2022.
- Sodium-glucose cotransporter 2 inhibitor use alone increased from 2.8% to 12.2% over the same period.
- Incident use of GLP-1 receptor agonists and/or SGLT2 inhibitors following a new diagnosis of atherosclerotic cardiovascular disease grew from 5.9% to 17.0% from 2018 to 2022.
- For GLP-1 receptor agonists alone, incident use rose from 3.6% to 7.8%, while SGLT2 inhibitors alone increased from 1.8% to 7.0%.
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Key numbers
27.1%
Increase in GLP-1 RA and SGLT2i Use
Proportion of patients with T2D and ASCVD prescribed GLP-1 RAs or SGLT2is in 2022.
17.0%
Incident Use After ASCVD Diagnosis
Proportion of patients with T2D newly prescribed GLP-1 RAs or SGLT2is in 2022 after ASCVD diagnosis.
9.2%
Prevalent Use in 2018
Proportion of patients with T2D and ASCVD prescribed GLP-1 RAs or SGLT2is in 2018.