The lancet. Psychiatry

Starting GLP-1 drugs and the risk of psychiatric hospital visits in US adults with schizophrenia and type 2 diabetes

Updated

Abstract

The study investigates the relationship between GLP-1 receptor agonist initiation and psychiatric hospitalization in adults with schizophrenia and type 2 diabetes.

  • Individuals with schizophrenia often experience ongoing psychotic symptoms despite treatment.
  • Schizophrenia is linked to significant metabolic dysregulation.
  • The potential psychiatric benefits of GLP-1 receptor agonists alongside their effects on metabolism are currently unclear.
  • Comparisons will be made between GLP-1 receptor agonists and other diabetes medications, including DPP-4 inhibitors and SGLT2 inhibitors.

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