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Abstract
Among 35,572 patients, semaglutide was associated with a lower risk of major adverse cardiovascular events compared to dulaglutide.
- Semaglutide was linked to a risk reduction in major adverse cardiovascular events (MACE) with a hazard ratio of 0.85.
- Expanded MACE, which includes hospitalization for heart failure and revascularization, showed a similar risk reduction for semaglutide (HR 0.92).
- All-cause mortality risk was lower for patients taking semaglutide (HR 0.81) compared to those on dulaglutide.
- Patients on semaglutide experienced a reduced risk of stroke (HR 0.82) and revascularization (HR 0.93).
- Liraglutide also demonstrated a lower risk of MACE (HR 0.84) and all-cause mortality (HR 0.79) compared to dulaglutide.
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