Safety and Effectiveness of Glucagon-like Peptide-1 Receptor Agonists in Inflammatory Bowel Disease

Dec 24, 2024The American journal of gastroenterology

Safety and Benefits of Glucagon-like Peptide-1 Drugs in Inflammatory Bowel Disease

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Abstract

Among 120 patients with inflammatory bowel disease, gastrointestinal side effects were reported in 11.5% of those treated with glucagon-like peptide receptor agonists.

  • Semaglutide was associated with significant weight reduction in patients.
  • C-reactive protein levels decreased after one year of treatment.
  • No differences were found in IBD-related hospitalizations or endoscopic scores.

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