Effects of glucose ingestion or glucose infusion on fuel substrate kinetics during prolonged exercise

Jan 1, 1994European journal of applied physiology and occupational physiology

How Eating or Infusing Glucose Affects Fuel Use During Long Exercise

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Abstract

Glucose ingestion significantly increased plasma insulin concentrations to 12.9 mU.l-1 compared to 4.8 mU.l-1 with glucose infusion.

  • Total rates of plasma glucose oxidation were higher with carbohydrate ingestion (9.5 mmol.125 min-1 kg FFM-1) compared to glucose infusion (6.2 mmol.125 min-1 kg FFM-1).
  • Carbohydrate oxidation rates also increased with ingestion, reaching 37.2 mmol.125 min-1 kg FFM-1 versus 24.1 mmol.125 min-1 kg FFM-1 with infusion.
  • Fat oxidation contributed more to energy production during glucose infusion (51%) than with carbohydrate ingestion (18%).
  • Both methods maintained similar plasma glucose concentrations, with ingestion at 5.3 mmol.l-1 and infusion at 5.0 mmol.l-1.

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