Genomics, proteomics & bioinformatics

How the Gut-Brain Connection May Influence the Cancer-Immune Response Cycle

Updated

Abstract

Gut microbiota-derived signals may influence cancer immunity through a complex regulatory framework.

  • The cancer-immunity cycle can be disrupted by tumor evasion of critical steps.
  • Gut-brain axis signals are associated with the regulation of cancer immunity.
  • Impacts of gut microbiota on cancer immunity may vary based on context.
  • Findings suggest potential direct interactions between microbiota and the immune system.
  • Most evidence regarding these mechanisms is currently preclinical and limited.

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