New Approaches to Treat Disease by Influencing Gut-Brain Communication from Understanding to Patient Care

Alterations in the gut microbiota have been reported in various neurological, psychiatric, and metabolic disorders.

• The gut-brain axis is a communication network connecting the gut and the central nervous system.
• Gut microbiota and its metabolites may influence neurotransmitter signaling, inflammation, barrier function, and host metabolism.
• Disruptions in microbiota communication pathways could have implications for health and disease.
• Current intervention strategies include microbiota modulation, dietary changes, neural and immunomodulatory approaches, and traditional medicine.
• The review emphasizes the need for further research on the evidence and safety of gut-brain-axis interventions.

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