Using Gut-Brain Communication as a New Treatment Approach for Stress-Related Tumors

Chronic psychological stress can significantly worsen tumor initiation and progression.

• Stress is linked to neuroendocrine dysregulation and tumor-associated immune suppression.
• It may disrupt gut microbiota balance, resulting in metabolic changes that affect tumors.
• The microbiota-gut-brain axis is a key pathway connecting stress to cancer development.
• A concept called 'gut-brain coherence' describes the balance between gut microbes, hormones, and immune function.
• Proposed strategies include microbial interventions, behavioral changes, and targeted medications to restore this balance.

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