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Gut, brain, and immune system interactions: using probiotics to deliver medicine for brain diseases
Updated
Abstract
Disruptions in the microbiome have been linked to chronic inflammation, which may contribute to neurological conditions.
- The gut-brain-immune (GBI) axis connects gut microbes, neural tissue, and immune cells and is critical for human health.
- Chronic inflammation associated with microbiome disruptions is observed in neurological diseases like Parkinson's and Alzheimer's.
- Novel therapeutic strategies are being explored to modulate the GBI axis for disease treatment.
- Live biotherapeutics, including engineered probiotics, could serve as next-generation drug delivery systems.
- These live microorganisms may be designed to deliver therapeutic compounds to influence immune responses and reduce inflammation.
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