Gut Microbiome's Possible Influence on Alzheimer's Disease

Sixteen gut bacterial taxa are associated with a reduced risk of Alzheimer's disease, while twelve taxa are linked to an increased risk.

• A two-sample Mendelian randomization analysis was conducted to explore the relationship between gut microbiota and Alzheimer's disease.
• Certain gut bacteria from the phylum Tenericutes and classes Bacilli and Clostridia are linked to a lower risk of Alzheimer's disease.
• The presence of 12 specific gut bacterial taxa, including those from class Actinobacteria and Betaproteobacteria, is correlated with a higher risk of Alzheimer's disease.
• Observations indicate that these gut bacteria may have a causal influence on Alzheimer's disease risk.

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