Gut Microbiome in Alzheimer’s Disease: from Mice to Humans

Oct 15, 2024Current neuropharmacology

Changes in Gut Bacteria Linked to Alzheimer's Disease in Mice and People

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Abstract

Changes in the gut microbiome are associated with the accumulation of amyloid beta in Alzheimer's disease.

  • Gut dysbiosis may influence the development and progression of Alzheimer's disease.
  • Increased amyloid beta deposition is linked to alterations in gut microbiome composition.
  • Cognitive impairment could be related to changes in the gut microbiome.
  • Metabolites produced by the gut microbiome may play a role in Alzheimer's disease pathology.
  • Potential therapies include antibiotics, prebiotics, probiotics, fecal microbiota transplantation, and dietary interventions.

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