Full text is available at the source.
Diversity and composition of gut microbiome of cervical cancer patients: Do results of 16S rRNA sequencing and whole genome sequencing approaches align?
Gut bacteria variety in cervical cancer patients: Comparing two DNA sequencing methods
AI simplified
Abstract
Comparative indices showed high congruence between 16S ribosomal RNA gene sequencing and shotgun metagenome sequencing.
- The most abundant genera identified by 16S and WMS did not overlap.
- Overlap was observed at the Phylum level, which was expected.
- Relative abundances of individual genera correlated poorly between the two methodologies, with all P-values greater than 0.05.
- Hierarchical clustering revealed overlapping enterotypes from both sequencing analyses.
- Both methods agreed on demographic variables related to the patient population.
AI simplified