Comprehensive Physiology

Changes in Gut Microbes in Brain Degenerative Diseases: How They Work, Treatment Possibilities, and Medical Views

Updated

Abstract

The gut microbiome produces various metabolites that can influence brain function.

  • Disruptions in the intestinal microbiota may be linked to neurological conditions.
  • The central nervous system can affect digestive functions through specific hormonal pathways.
  • Gut microbiota can influence brain function through metabolites that interact with the central nervous system.
  • Only certain metabolites can cross the blood-brain barrier to affect the central nervous system.
  • Microbial metabolites can activate specific receptors that modulate neural signaling and provide protective effects for neurons.

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