BMC neurologyJun 29, 2026

Differences in gut bacteria between stroke patients and healthy people

Gut-Brain Axis Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated Jun 30, 2026

Abstract

Gut microbiota composition may differ significantly between ischemic stroke patients and healthy controls.

Ischemic stroke is a major cause of death and disability globally.
Imbalances in gut microbiota, known as dysbiosis, are linked to increased neuroinflammation.
Dysbiosis is associated with worse outcomes in stroke patients.
The study investigates potential microbial changes related to ischemic stroke.

Simplified

Ischemic stroke is a leading cause of mortality and disability worldwide. Emerging evidence suggests that the gut microbiota, acting through the gut-brain axis, may play a critical role in stroke pathophysiology. Dysbiosis, an imbalance of gut microbiota, has been associated with neuroinflammation and poor stroke outcomes. This study aimed to compare gut microbiota composition in ischemic stroke patients versus healthy controls to explore potential microbial changes linked to stroke.

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Funding

Competing interests

Declarations. Ethics approval and consent to participate: The study was conducted in accordance with the declaration of Helsinki and was approved by the institutional review board and ethics committee of Tabriz Islamic Azad University Faculty of Medicine (IR.IAU.TABRIZ.REC.1403.060). Written informed consent was acquired from all the participants at the time of participation. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

PubMed

Differences in gut bacteria between stroke patients and healthy people

Abstract

Full Text

Funding

Competing interests

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