Biopsychosocial science and medicine

Gut Bacteria and Mental Stress in Fibromyalgia: A Systematic Review

Updated

Abstract

Ten studies were analyzed, revealing significant differences in gut microbiota composition between fibromyalgia patients and healthy controls.

  • Most studies indicated an imbalance in gut microbial communities among fibromyalgia patients.
  • Alterations in gut microbiota were linked to higher levels of psychological distress, including emotional and cognitive symptoms.
  • Differences in gut permeability were observed in fibromyalgia patients compared to healthy controls.
  • The findings suggest potential impairment in the gut-brain axis regulation in stress-related pain conditions.
  • Further research is required to understand the microbiota-gut-brain axis's role in the mechanisms of fibromyalgia.

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