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Correlations between gut microbiota and serum metabolomics in patients with neurogenic rosacea
Links between gut bacteria and blood metabolism in people with nerve-related rosacea
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Abstract
Analysis revealed 56 differentially abundant metabolites in patients with neurogenic rosacea compared to healthy controls.
- Patients with neurogenic rosacea exhibited significant dysbiosis in gut microbiota.
- Increased abundances of Lachnospiraceae, Veillonellaceae, and Clostridiaceae were observed, while Prevotellaceae and Bifidobacteriaceae decreased.
- Strong positive correlations were found between specific serum metabolites and gut microbial taxa.
- Notable correlations included 3,4-dihydroxyphenylacetic acid with Bifidobacterium (r = 0.7307) and Lactobacillus (r = 0.6898).
- These findings indicate complex interactions between metabolic dysregulation and gut microbial imbalances in neurogenic rosacea.
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