Comparing high doses of THC, psilocybin, and placebo during a classic psychedelic therapy session

High doses of Delta-9-tetrahydrocannabinol (Δ9-THC) may evoke psychedelic-like experiences in some individuals.

• The specific doses of Δ9-THC that lead to these effects are not well defined.
• There is limited understanding of the nature and characteristics of the psychedelic-like experiences induced by Δ9-THC.
• The variability in individual responses to high doses of Δ9-THC is noted.

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