Full text is available at the source.
Human melatonin suppression by light: a case for scotopic efficiency
How human melatonin reduction by light relates to night vision sensitivity
AI simplified
Abstract
A dose-dependent response of acute melatonin suppression to light was identified in human adult males.
- Melatonin suppression was observed across two illuminances and two spectral power distributions during nighttime sessions.
- Photopic illuminance, based on cone activity, was not a reliable predictor of melatonin suppression.
- Scotopic illuminance, linked to rod activity, showed a nearly monotonic relationship with melatonin suppression.
- Rod cells or a rod-dominated mechanism may play a significant role in regulating melatonin levels in humans.
- Other mechanisms, including potential novel photoreceptors, cannot be entirely excluded as contributors to melatonin regulation.
AI simplified