The Effect of β-Hydroxy-β-Methylbutyrate on Aerobic Capacity and Body Composition in Trained Athletes

Feb 6, 2016Journal of strength and conditioning research

Beta-Hydroxy-Beta-Methylbutyrate's effects on endurance and body makeup in trained athletes

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Abstract

Supplementation with β-hydroxy-β-methylbutyrate (HMB) resulted in a significant increase in fat-free mass by 0.2 kg compared to a decrease of 1.0 kg in the placebo group.

Fat mass decreased by 0.8 kg in the HMB group, while it increased by 0.8 kg in the placebo group.
Maximal oxygen uptake increased by 0.102 L·min in the HMB group versus a decrease of 0.063 L·min in the placebo group.
Time to reach ventilatory threshold increased by 1.0 minute with HMB supplementation, while it decreased by 0.4 minutes in the placebo group.
Threshold load at ventilatory threshold improved by 20 W in the HMB group compared to a decrease of 7 W in the placebo group.
Threshold heart rate at ventilatory threshold rose by 8 beats per minute in the HMB group, while it fell by 1 beat per minute in the placebo group.
Testosterone levels increased in the HMB group, while cortisol levels were elevated in both groups.

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Durkalec-Michalski, K and Jeszka, J. The effect of β-hydroxy-β-methylbutyrate on aerobic capacity and body composition in trained athletes. J Strength Cond Res 30(9): 2617-2626, 2016-The aim of this study was to investigate whether supplementation with β-hydroxy-β-methylbutyrate (HMB) affects body composition, aerobic capacity, or intramuscular enzymes activity, as well as in anabolic and/or catabolic hormones and lactate concentrations. A cohort of 58 highly trained males was subjected to 12-week supplementation with HMB (3 × 1 gHMB·d) and a placebo (PLA) in randomized, PLA controlled, double-blind crossover trials, with a 10-day washout period. Body composition and aerobic capacity were recorded, whereas the levels of creatine kinase, lactate dehydrogenase, testosterone, cortisol, and lactate, as well as the T/C ratio, in blood samples were measured. After HMB supplementation, fat-free mass increased (+0.2 kgHMB vs. -1.0 kgPLA, p = 0.021), with a simultaneous reduction of fat mass (-0.8 kgHMB vs. +0.8 kgPLA, p < 0.001). In turn, after HMB supplementation, in comparison to PLA, maximal oxygen uptake (V[Combining Dot Above][Combining Dot Above]O2max: +0.102 L·minHMB vs. -0.063 L·minPLA, p = 0.013), time to reach ventilatory threshold (VT) (TVT: +1.0 minHMB vs. -0.4 minPLA, p < 0.0001), threshold load at VT (WVT: +20 WHMB vs. -7 WPLA, p = 0.001), and the threshold heart rate at VT (HRVT: +8 b·minHMB vs. -1 b·minPLA, p < 0.0001) increased significantly. Analysis of the tested biochemical markers shows significant differences only in relation to the initial concentration. In HMB group, testosterone levels increased (p = 0.047) and in both groups (HMB: p = 0.008; PLA: p = 0.008) higher cortisol levels were observed. The results indicate that supplying HMB promotes advantageous changes in body composition and stimulates an increase in aerobic capacity, although seeming not to significantly affect the levels of the analyzed blood markers.

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The Effect of β-Hydroxy-β-Methylbutyrate on Aerobic Capacity and Body Composition in Trained Athletes

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