A hyperpolarizing rod bipolar cell in the sea lamprey, Petromyzon marinus

Mar 23, 2022The Journal of experimental biology

A rod bipolar cell that reduces activity in the sea lamprey

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Abstract

Lamprey rod bipolar cells are OFF cells with little or no cone input and a morphology similar to rod photoreceptors.

  • Lamprey possess rod bipolar cells that predominantly receive input from rods rather than cones.
  • These rod bipolar cells exhibit a morphology and spectral sensitivity closely resembling rod photoreceptors.
  • In conditions of background light that saturate rods, these rod bipolar cells are also saturated and unable to respond to light increments.
  • Findings suggest that early vertebrate ancestors may have had a more flexible retinal structure than previously recognized.

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