Journal for immunotherapy of cancer

IL7R mRNA treatment boosts cancer-fighting T cells and slows tumor growth in animal models

Updated

Abstract

IL7R mRNA therapy may enhance antitumor immunity and improve tumor control.

  • Interleukin-7 receptor (IL7R) signaling is essential for T-cell survival and immune function.
  • Increasing IL7R expression through mRNA delivery could be a potential therapeutic strategy.
  • The effectiveness of IL7R mRNA therapy was examined in preclinical cancer models.

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Full Text

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