International reviews of immunology

Aging immune system decline and organ communication problems: Possible benefits of algae-based compounds and nutrition for healthy aging

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Abstract

Aging-associated immunosenescence disrupts various immune pathways, leading to impaired interactions between the immune system and organs.

  • Immunosenescence is linked to geriatric conditions such as neurodegenerative disorders, chronic inflammation, and metabolic syndromes.
  • The immune-organ axis connects immune dysregulation to specific organ dysfunction.
  • Nutritional interventions may modulate immune pathways through mechanisms like autophagy induction, inflammation resolution, and cellular repair promotion.
  • Technological solutions for stabilization and delivery could enhance the efficacy of nutritional interventions.
  • Integrative approaches are needed to address immune dysfunction and improve health outcomes in aging populations.

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