PloS one

Changes in heart and metabolism health and energy balance after stopping semaglutide treatment

Updated

Abstract

GLP-1 receptor agonists like semaglutide can lead to significant weight loss in patients with obesity.

  • Weight loss associated with semaglutide can be substantial.
  • Improvement in cardiometabolic risk factors is observed during treatment.
  • Most patients experience weight regain after stopping semaglutide.
  • The beneficial effects on cardiometabolic health may reverse following withdrawal.

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Full Text

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Funding

Competing interests

Protocol paper NA.
PubMed

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