Trends in molecular medicine

A lab test to predict when PD-1 blocker treatments may not work

Updated

Abstract

A new functional assay may accurately predict immune checkpoint inhibitor response.

  • Most patients treated with immune checkpoint inhibitors do not respond to the treatment.
  • There is a significant demand for predictive biomarkers to identify which patients will benefit from immune checkpoint inhibitors.
  • The reported functional assay could provide insights into the likelihood of treatment response.

Simplified

Full Text

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Funding

Competing interests

Declaration of Interests S.K. is an inventor of several patents in the field of immuno-oncology. S.K received research support from TCR2 Inc. and Arcus Bioscience for work unrelated to this manuscript, and Honoria from TCR2 Inc., Novartis and GSK.
PubMed

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