Rheumatology (Oxford, England)

Aging-related inflammation changes the immune system in IgG4-related eye and salivary gland inflammation

Longevity & Aging Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated

Abstract

IgG4-related disease (IgG4-RD) predominantly affects middle-aged and elderly individuals.

  • The immune architecture in lesions associated with IgG4-RD may differ based on age.
  • Aging could influence the immune response in patients with IgG4-RD.
  • Current understanding of how aging affects IgG4-RD lesions is limited.

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