Long-term benefits of insulin pump therapy versus multiple daily injections in type 2 diabetes over 12 months

At the end of a 6-month randomized phase, pump therapy led to a significantly greater reduction in HbA1c compared to multiple daily injections (MDI).

• The mean HbA1c reduction with pump therapy was -1.1 ± 1.2%, compared to -0.4 ± 1.1% for MDI.
• After switching from MDI to pump therapy, the HbA1c reduction in the MDI-pump group was 0.8%, resulting in identical final HbA1c levels in both groups.
• Total daily insulin dose was 20.4% lower with pump therapy during the randomized phase and remained stable in the continuation phase.
• By 12 months, total daily insulin doses were equivalent in both groups.
• No differences in weight gain or ketoacidosis were observed between the two treatment groups.

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