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Abstract
Sepsis disrupts circadian rhythm, leaving lasting molecular traces and circadian insensitivity to jet lag.
- Circadian rhythm disruption may persist even after recovery from the acute phase of sepsis.
- Residual circadian dysfunction is associated with lasting molecular changes.
- The core mechanisms behind the ongoing circadian issues following sepsis are not yet understood.
- Identifying biomarkers of circadian dysfunction could aid in developing targeted interventions.
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